Cortical circuits, their functional connectivity and cognitive processes in the comorbid disorder; obsessive compulsive and major depressive

Abstract

The present work makes a review of the literature through which rumination and repetitive negative thoughts are explored as mechanisms for maintaining symptoms in patients with obsessive compulsive disorder (OCD) and / or major depressive disorder (MDD). It is taken as a sample, studies dating between 2010 and 2018 that measure cortical activation patterns related to cognitive control processes, and self-referential processing,5 memory coding while performing tasks,2 including among their methods, resonance functional magnetic,10 blood oxygenation levels3 and comparative in terms of participants; subjects with depression vs. control diagnosis,6 comparative regarding the application of drug or behavioral treatment (1), studies using neuroticism questionnaires,2 research-based theorists.4 It is concluded that the observable phenomenology of both disorders when presented together, integrate harmonic connectivity patterns with the same basic transdiagnotic functions, compatible with potentials that run in parallel by jointly overactivating certain brain areas, whose altered mode of functioning is unveils it as the base substrate on which, it is possible to explain alterations of inhibitory control processes such as executive functions, operational memory and deregulation of the dream architecture.